论文部分内容阅读
胺碘酮(Amiodarone)是以Ⅲ类药作用为主的心脏离子多通道阻滞剂,兼备Ⅰ、Ⅱ、Ⅳ类抗心律失常药物的电生理作用。胺碘酮为广谱抗心律失常药,药理学特征复杂,作用多样,可引起多种不良发应。由于其主要通过肝脏细胞色素P450代谢,约有15%～50%患者在治疗过程中出现血清转氨酶升
Amiodarone is a kind of multi-channel blocker of cardiac ion which mainly acts as class III drugs and has the electrophysiological effects of antiarrhythmic drugs of type I, II and IV. Amiodarone is a broad-spectrum anti-arrhythmic drug, pharmacological characteristics of complex, diverse, can cause a variety of adverse reactions. Due to its mainly through the liver cytochrome P450 metabolism, about 15% to 50% of patients in the course of treatment, serum transaminase liter