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近20年,国内外学者对精神分裂症患者血清免疫球蛋白(Ig)作了大量研究,但脑脊液(CSF)中Ig方面研究较少。我们对18例精神分裂症患者作了CSF中Ig微球蛋白(简称β_2-m)指标测定,现将结果报告如F。资料与方法一般资料随机选择了符合苏州会议制定的精神分裂症诊断标准,不伴有躯体疾患,也未接受免疫抑制剂治疗的18名男性住院精神分裂症患者。年龄23～51岁,平均28.3岁。病程1个月～31年。临床类型:偏执型8例,未定型4例,衰退型6例。7例采用氯丙嗪口服,1例采用氯氮平口服治疗。对照组为正常健康人。实验方法全部标本均采用放射免疫分析法测定。试剂盒由上海放射免疫研究所提供的
In the recent 20 years, scholars at home and abroad have done a lot of research on serum immunoglobulin (Ig) in patients with schizophrenia, but there are few studies on Ig in cerebrospinal fluid (CSF). We made 18 cases of schizophrenia in patients with CSF Ig microglobulin (referred to as β_2-m) index determination, the results are reported as F. Materials and Methods General Information A total of 18 male inpatients with schizophrenia who were randomly selected to meet the diagnostic criteria for schizophrenia developed by the Suzhou meeting, without physical illness, and without immunosuppressive agents. Age 23 ~ 51 years old, with an average of 28.3 years old. Duration of 1 month to 31 years. Clinical type: paranoid type in 8 cases, unconfined type in 4 cases, recessive type in 6 cases. 7 cases were treated with chlorpromazine and 1 case was treated with clozapine. The control group was normal healthy people. Experimental methods All specimens were determined by radioimmunoassay. Kit provided by the Shanghai Institute of Radioimmunology