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持续性面肌阵挛(CFM)为不随意的波状起伏向面部扩展的蠕虫样运动,有特征性肌电活动。以多发性硬化(MS)和脑干肿瘤多见,确切病因未明,提示与核上、核性及核下损害有关。本文报告12例有CFM的MS,结合MRI检查以探讨随意运动障碍的发病机理。 自确诊MS至发生CFM平均5.1年,单侧CFM9例,双侧CFM3例,其中2例于病后7~14天由单侧发展为双侧。4例呈持续强直痉挛,4例因同向偏斜使CFM加重。9例CFM持续3周~1年后消失,2例分别持续24、80周仍不中止,1例CFM虽消失,但不能确定CFM发生时间。2例分别于2周,4年后复发。12例皆于CFM期间做
Continuous myoclonus (CFM) is a worm-like movement that spreads involuntarily to the face and exhibits characteristic myoelectrical activity. To multiple sclerosis (MS) and brain stem tumors more common, the exact cause is unknown, suggesting that the nuclear, nuclear and nuclear damage. This article reports 12 cases of CFM MS, combined with MRI examination to explore the pathogenesis of voluntary dyskinesia. Since the diagnosis of MS to CFM an average of 5.1 years, unilateral CFM 9 cases, bilateral CFM 3 cases, of which 2 cases 7 to 14 days after the disease from unilateral to bilateral. 4 cases showed persistent tonic spasm, and 4 cases of CFM aggravated due to the same direction. 9 cases of CFM disappeared after 3 weeks to 1 year, 2 cases continued for 24 and 80 weeks, respectively. The CFM disappeared, but CFM was not confirmed. 2 cases were in 2 weeks, 4 years after the recurrence. All 12 cases were done during CFM