【摘 要】
:
Chlorothiazole ring,as a substituted heterocycle,frequently occurred in structures of various insecticides,and brought positive effect on bioactivity.In purpose
【机 构】
:
Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and
【出 处】
:
Chinese Chemical Letters
论文部分内容阅读
Chlorothiazole ring,as a substituted heterocycle,frequently occurred in structures of various insecticides,and brought positive effect on bioactivity.In purpose to find novel neonicotinoids,a series of pyrrole-and dihydropyrrole-fused neonicotinoid analogs containing chlorothiazole ring were synthesized for the first time.Results of the following biological assays showed that compounds 5a-c achieved good insecticidal activity against Aphis craccivora,and compound 5h exhibited good activity against Nilaparvata lugens.
Chlorothiazole ring, as a substituted heterocycle, frequently occurred in structures of various insecticides, and brought positive effect on bioactivity. Purpose to find novel neonicotinoids, a series of pyrrole-and dihydropyrrole-fused neonicotinoid analogs containing chlorothiazole ring were were for the first time . Results of the following biological assays showed those compounds 5a-c achieved good insecticidal activity against Aphis craccivora, and compound 5h exhibited good activity against Nilaparvata lugens.
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