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探讨COPD夜间睡眠结构及血氧饱和度变化 ,以期为临床提供诊疗依据。方法 :应用多导睡眠记录仪进行睡眠监测 ,测定项目包括脑电图、眼动图、心电图、颏肌肌电图、口鼻气流、胸腹呼吸运动、血氧饱和度共 7个参数 ;结果 :与健康人组比较 ,COPD组Ⅰ期、Ⅱ期睡眠时间无显著性差异 (P >0 .0 5 ) ,但Ⅲ期、Ⅳ期时间、人睡后醒觉次数大于 5分钟 ,浅睡眠的比率、深睡眠的缺乏率及REM缺乏率均有显著性差异 (P <0 .0 1～ 0 .0 0 1 )。COPD组氧饱和度降低≥ 4% ,氧减饱和度 85 %～ 5 0 %频率分布 ,夜间最高、最低和平均氧饱和度、SIT85 %、△SaO2 均与健康人有显著性差异 (P <0 .0 0 1 )。结论 :COPD患者组存在有严重的睡眠呼吸紊乱和睡眠的破碎 ,同时存在有严重的夜间低氧血症和呼吸暂停 ,因此 ,加强对COPD患者夜间睡眠和SaO2 监测 ,对于提高患者的生命质量具有十分重要的意义。
To investigate the changes of night sleep structure and oxygen saturation in COPD in order to provide clinical diagnosis and treatment basis. Methods: The polysomnography recorder was used for sleep monitoring. The items of measurement included 7 parameters: electroencephalogram, eye pattern, electrocardiogram, chin muscle EMG, nasal airflow, chest and abdomen respiratory activity and oxygen saturation. Results Compared with the healthy group, there was no significant difference between the first and second phase of COPD sleep (P> 0.05), but the third and fourth phase of the time, the number of people awake after sleeping more than 5 minutes, light sleep There was a significant difference in the rate, lack of deep sleep and REM deficiency (P <0.01 ~ 0.010). Oxygen desaturation in COPD group was more than 4%, oxygen desaturation was 85% ~ 50%, nighttime highest, lowest and average oxygen saturation, SIT85%, △ SaO2 were significantly different from healthy people (P <0 .0 0 1). CONCLUSIONS: COPD patients have severe sleep-disordered breathing and disrupted sleep accompanied by severe nocturnal hypoxemia and apnea, thus enhancing nighttime sleep and SaO2 monitoring in patients with COPD and improving the quality of life of patients with Very important meaning.