论文部分内容阅读
近十年来,随着细胞生物学及分子生物学研究的不断深入,人们对多肽类生长因子的生化特性和生物学作用的认识愈趋广泛。并认识到它们能参与一些疾病的病理过程,也逐渐认识到很多多肽生长因子参与了肾小球肾炎中及炎症后的组织重建和生长修复。本文主要综述多肽生长因子在肾脏中的表达及其在生理、病理过程中的作用。多肽生长因子的定义、分类及其作用特点多肽生长因子(Polypeptide growth factors)是调控细胞生长的肽类物质,可由体内很多细胞产生,具有重要生理病理及治疗作用。所有多肽生长因子都具有下列共同的特
In the past decade, with the deepening of the research on cell biology and molecular biology, people have become more aware of the biochemical characteristics and biological effects of polypeptide growth factors. They also realized that they could participate in the pathological process of some diseases, and gradually realized that many polypeptide growth factors were involved in the reconstitution and growth repair of glomerulonephritis and after inflammation. This article mainly reviews the expression of polypeptide growth factor in the kidney and its role in physiological and pathological processes. The definition, classification and functional characteristics of polypeptide growth factors Polypeptide growth factors are peptides that regulate cell growth. They can be produced by many cells in the body and have important physiological, pathological and therapeutic effects. All polypeptide growth factors have the following common characteristics