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目的分析饮茶型氟中毒居民经砖茶摄氟量与X线氟骨症病情关系。方法选择内蒙古克什克腾旗饮茶型氟中毒病区达来诺日镇罕达罕、哈达英格嘎查为调查点,对调查点20～70岁居民进行X线氟骨症检查及砖茶饮料含氟量检测,计算经砖茶日摄氟量、相对总摄氟量[经砖茶饮料日摄氟量~(-3)×365 d×(年龄-20)];X线氟骨症诊断采用WS192-2008《地方性氟骨症诊断标准》,砖茶饮料含氟量检测采用离子选择电极法;分析经砖茶日摄氟量、相对总摄氟量与X线氟骨症检出率关系。结果调查点居民X线氟骨症检出率为61.7%(82/133),X线重度氟骨症为3.8%(5/133),调查点为地方性氟中毒重病区。调查点砖茶饮料含氟量(2.55±1.29)mg/L;每人每天经砖茶摄氟量(6.92±5.29)mg,相对总摄氟量(64.07±59.91)g/人,经砖茶摄氟量、相对总摄氟量与X线氟骨症检出率均呈正相关(R分别为0.908、0.878,F分别为14.09、10.13,P<0.05)。每人每天经砖茶摄氟量≤3.0 mg与>3.0 mg各组X线氟骨症检出率比较无显著性差异,相对总摄氟量>15 g/人X线氟骨症检出率(57.69%)是显著升高的节点(t=5.08,P<0.05),如按40岁年龄计算,每人每天经砖茶摄氟量为2.05 mg[15~3÷365÷(40-20)],相对总摄氟量≤15g/人与>15.0 g/人各组X线氟骨症检出率比较均有显著性差异(χ~2值分别为5.08、6.83、10.78、11.32,P<0.05)。结论经砖茶摄氟量、相对总摄氟量与X线氟骨症检出率均呈显著正相关,相对总摄氟量≥15 g/人X线氟骨症检出率显著增高,提示每人每天经砖茶摄氟量应≤2.0 mg。
Objective To analyze the relationship between fluorosis of fluorosis by drinking brick tea and fluorosis of X-ray. Methods Select Khan Keteng Banner, Inner Mongolia drinking tea-type fluoride poisoning area to the town of Norfolk Han and Daya Ge check as a survey point of 20 to 70-year-old residents survey X-ray bone disease examination and brick tea Determination of fluorine content in beverages, calculating the amount of fluorine absorbed by brick tea, the relative total amount of fluoride [Flux of bricks by drinking tea on a daily basis ~ (-3) × 365 d × (age -20)]; X-ray diagnosis of skeletal bone using WS192-2008 “diagnostic criteria of endemic fluorosis”, brick tea drink fluorine detection method using ion-selective electrode method; analysis by brick tea on the amount of fluoride, the relative total fluoride content and X-ray skeletal disease detection rate. Results The detection rate of X-ray skeletal fluorosis was 61.7% (82/133) and X-ray severe skeletal fluorosis was 3.8% (5/133) in the survey area. The survey area was endemic to fluorosis. The content of fluoride in brick tea beverage was (2.55 ± 1.29) mg / L at the survey point; the amount of fluoride (6.92 ± 5.29) mg and the relative total fluoride (64.07 ± 59.91) g / , And the relative total fluoride intake was positively correlated with the detection rate of X-ray skeletal fluorosis (R = 0.908,0.878, F = 14.09,10.13 respectively, P <0.05). Per person per day by bricks tea fluoride content ≤ 3.0 mg and> 3.0 mg X-ray skeletal fluorosis detection rate was no significant difference, the relative total fluoride intake> 15 g / person X-ray skeletal detection rate ( 57.69%) were significantly increased nodes (t = 5.08, P <0.05). According to the age of 40 years, the amount of fluoride per potash tea per day was 2.05 mg [15-3 ÷ 365 ÷ (40-20)] , And the relative detection rate of fluorosis of X-ray in all groups with fluoride content ≤15g / person and> 15.0g / person had significant difference (χ ~ 2 = 5.08,6.83,10.78,11.32, P <0.05 ). Conclusion The amount of fluoride taken by brick tea, the relative total fluoride and X-ray detection rate of skeletal disease were significantly positive correlation, the relative total fluoride dose ≥ 15 g / person X-ray skeletal fluorosis detection rate was significantly increased, suggesting that each Per person by brick tea fluoride intake should be ≤ 2.0 mg.