糖皮质激素为一种常用抗炎药,具有强大的抗炎和免疫抑制功能,临床上广泛用于炎症及自身免疫性疾病,但如使用不当或在少数敏感个体,则可诱发类固醇肌病。大量对类固醇肌病病因学和机制的研究,推动了对这一疾病的诊断和治疗,从而增加了对该病的整体认识。以下就类固醇肌病的相关发病机制、临床特点、诊断和治疗手段作一综述。 Glucocorticoids, a commonly used anti-inflammatory drug, have powerful anti-inflammatory and immunosuppressive functions and are widely used clinically in inflammatory and autoimmune diseases. However, glucocorticoid may induce steroid myopathy if used improperly or in a few sensitive individuals. Extensive research into the etiology and mechanisms of steroid myopathy has prompted the diagnosis and treatment of this disease, thereby increasing the overall awareness of the disease. The following steroid myopathy related pathogenesis, clinical features, diagnosis and treatment to be reviewed.