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当此Lieuwenhock描述精子的纪念日到来之际,作者回顾有关这个令人注目的细胞知识的进展,以作为300年来显微镜成就的估价。1667年借助简陋的显微镜描述了精子的一般形态及运动现象。十八和十九世纪用复合显微镜加深了这些认识,但对细胞内部结构的认识却很少。在过去25年内电子显微镜及其辅助技术,使对精子结构的分析达到了分子水平。顶体(Acrosome)已被确定为如象分泌粒和某些情况下的溶酶体那样系由高基氏器发生来的膜性细胞器。已弄清了它的水解酶,并描述了它在顶
As Lieuwenhock commemorates the anniversary of sperm, the authors review the progress of this remarkable cellular knowledge as an estimate of the achievements of the microscope over the past 300 years. In 1667 with a crude microscope describes the general shape and movement of sperm phenomenon. The eighteenth and nineteenth centuries have deepened these understanding with the compound microscope, but little understanding of the internal structure of the cell. In the past 25 years, electron microscopy and its assistive technologies have enabled the analysis of sperm structures to reach molecular levels. Acrosome has been identified as a membranous organelle that occurs as a Kupffer, as secretosomes and, in some cases, lysosomes. It has elucidated its hydrolase and described it at the top