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作者收集 5项普伐他汀 (4 0mg/d)二级预防随机试验资料 ,总共观察 7390 0人 /年 ,均不同程度地加用了阿司匹林 ,多数混杂变量数据可用。应用多元回归模型对多种心血管疾病危险进行校正 ,分析普伐他汀和阿司匹林联合是否具有额外临床效益。结果显示 ,普伐他汀加阿司匹林组发生致
The authors collected five randomized trials of pravastatin (40 mg / d) for secondary prevention. A total of 7390 0 person-years were observed. Aspirin was added to varying degrees and most of the confounding variables were available. Multiple regression models were used to correct for a variety of cardiovascular risk and analyzed whether pravastatin and aspirin combination have additional clinical benefit. The results showed that pravastatin plus aspirin group caused