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由于一些有机氯化合物（包括一些农用杀虫剂）可能有弱的雌激素效应，因此被怀疑可能增加患乳腺癌的危险性，丹麦哥本哈根前瞻性人群研究中心的HoyerAP等，采用前瞻性研究方法，观察了患乳腺癌的危险性与血清中有机氯化合物浓度的关系。作者收集了1976年参加哥本哈根市心脏研究
Since some organochlorine compounds (including some agricultural pesticides) may have weak estrogen effects and are therefore suspected of increasing the risk of breast cancer, HoyerAP et al. (Copenhagen, Denmark) used forward-looking research methods. The relationship between the risk of breast cancer and the concentration of organochlorine compounds in the serum was observed. The author collected 1976 participation in the Copenhagen City Heart Study