1.本文报告60例骨巨细胞瘤手术,男性33例、女性27例,平均31.75岁,21—40岁占75%。部位以四肢长骨端为多见,占78.33%,其中好发于膝部,占长骨端的68%。随访55的,有9例死亡,二例肺转移及3例局部复发。共占25.45%。2.病理:5年生存率Ⅰ级93.8%,Ⅱ级80.2%,Ⅲ级0,肿瘤间质细胞的形态与预后亦有关,F型5年生存率95%,H型75.9%。且H型及有血窦样结构者,肺转移较多。3.刮除加植骨术。复发率为13.3%,疗效较好,大块截除关节融合术,复发转移率为13.3%,截肢术主要用于Ⅲ级,但亦不能挽救生命。 1. This article reports 60 cases of giant cell tumor of bone, 33 males and 27 females, with an average of 31.75 years old, and 70% of those aged 21-40 years. The long bones of the extremities were more common in the site, accounting for 78.33%, of which it occurred in the knee, accounting for 68% of the long bone. At follow-up 55, there were 9 deaths, 2 lung metastases, and 3 local recurrences. A total of 25.45%. 2. Pathology: The 5-year survival rate was 93.8% for grade I, 80.2% for grade II, and grade 0. The morphology and prognosis of tumor stromal cells were also related. The 5-year survival rate of type F was 95%, and that of type H was 75.9%. H-type and sinusoid-like structure, more lung metastases. 3. Curing and bone grafting. The recurrence rate was 13.3%, and the curative effect was good. The mass resection and fusion was performed in 13.3% of the patients. The amputation technique was mainly used in Class III, but it also failed to save lives.