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1型糖尿病患者必须一天多次测量血糖水平,并自己注射胰岛素来阻止其血糖水平升高。这除了对患者的日常生活带来诸多不便和限制以外,常规注射胰岛素也很难精确地控制患者的血糖水平。研究人员在努力寻找改善1型糖尿病治疗的更好方法。其中一种方法,就是月能够监测血糖和释放胰岛素的健康胰岛细胞,取代胰腺中被摧毁的胰岛细胞。研究人员对几百种藻酸衍生物进行筛选后选定了经TMTD化学修饰的藻酸盐,然后把人胰岛细胞包于TMTD藻酸盐制成的胶
Patients with type 1 diabetes must measure their blood glucose levels several times a day and themselves inject insulin to prevent their blood sugar levels from rising. In addition to bringing inconvenience and limitation to the daily life of patients, it is also very difficult to accurately control the patient’s blood glucose level with conventional insulin injections. Researchers are trying to find better ways to improve the treatment of type 1 diabetes. One of the ways to do this is to replace healthy pancreatic islet cells with healthy islet cells that monitor blood sugar and release insulin on a monthly basis. After screening hundreds of alginate derivatives, the researchers selected the TMTD-chemically modified alginate and then encapsulated human islet cells in TMTD alginate gel