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6β-乙酰氧基去甲莨菪烷(6β-AN)是人工合成莨菪烷拟胆碱作用最强的化合物,有可能代替匹罗卡品用以治疗青光眼。本文就我校化学教研室项中等将外消旋体dl-6β-AN拆分后得的左、右旋光异构体进行药效动力学研究。
6β-Acetoxy norpene (6β-AN) is the most potent synthetic compound of tropane and cholinergic, which may replace piroctone to treat glaucoma. In this paper, the left and right optical isomers resolved by racemic dl-6β-AN were studied pharmacodynamically in the middle of Chemistry Department of our university.