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以β-苯乙胺和对硝基苯基溴乙基醚反应生成N-(对硝基苯氧乙基)β-苯乙胺和其重排产物N-(2-苯乙基)N-(2-羟乙基)-对硝基苯胺为例,研究分子内激活的亲核芳香取代反应——N-O型Smiles重排的动力学过程。
The reaction of β-phenylethylamine and p-nitrophenyl ethyl bromide to form N- (p-nitrophenoxyethyl) β-phenylethylamine and its rearrangement product N- (2-phenylethyl) N- (2-hydroxyethyl) -p-nitroaniline was used as an example to study the kinetics of intramolecular aromatic nucleophilic substitution-N-O Smiles rearrangement.