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系列培养基的应用使人们对人胚胎培养至囊胚期进行移植产生了兴趣。应用此新的系列培养基使培养至囊胚期的生存率提高,种植率(胎囊/每次移植)达50%,妊娠率达65%。1995年美国生殖医学会对助孕技术的年度报告提出多胎发生率达37%。且7%为三胎或三胎以上。孕母新生儿合并症增加,早产及长期病率高,围产死亡率为单胎10倍。应用此法可减少移植胚胎至2个,以减少多胎率。本文在美国科罗利多及加利福尼亚州二个试管婴儿中心,应用此系列培养至胚胎囊胚期进行移植,并观察其结果。自1998~1999年共174例。年龄<45岁,促卵泡成熟
The use of a series of media has led to interest in the transplantation of human embryos into blastocysts. With this new line of media, the survival rate increased from blastocyst to blastocyst up to 50% of implantation (gestational sac / per transplant) with a pregnancy rate of 65%. In 1995, the annual report of the American Society of Reproductive Medicine on assisted pregnancy suggested a multiple birth rate of 37%. And 7% for three or more tires. Maternal complications of newborns increased, premature birth and long-term morbidity, perinatal mortality was 10 times singleton. Use this method can reduce the transfer of embryos to 2, in order to reduce the multiple birth rate. In this paper, two tube-baby centers in Colorado, California and in California are used to culture the embryo blastocyst stage and to observe the results. A total of 174 cases from 1998 to 1999. Age <45 years old, follicle mature