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目的:探讨治疗围绝经期功能性失调子宫出血运用小剂量米非司酮联合去氧孕稀缺雌醇的有效性。方法:将我院2013年3月-2014年3月进行治疗的围绝经期功能失调性子宫出血的患者106例进行探究,将这106例患者随机的分成两个小组,分别为观察组和对照组,每组患者例数为53例。对照组患者在接受刮宫手术后采用去氧孕稀缺雌醇治疗,观察组的患者在接受刮宫手术后采用小剂量米非司酮联合去氧孕稀缺雌醇治疗。患者治疗后,对患者的治疗效果、子宫内膜厚度等进行对比。结果:在经过一段时间的治疗后,两组患者都取得了一定的治疗效果,观察组的治疗效果与对照组相比,其效果更加突出,组间差异统计学意义突出(P<0.05)。结论:在观察两组患者的治疗效果和各项指标后,看出观察组的治疗效果更佳,在治疗功能失调性子宫出血中,运用小剂量的米非司酮结合去氧孕稀缺雌醇效果好,而且副作用少,值得在临床上应用。
Objective: To investigate the efficacy of low dose of mifepristone combined with deoxyestradiol-oestradiol in the treatment of menopausal dysfunctional uterine bleeding. Methods: A total of 106 patients with peri-menopausal dysfunctional uterine bleeding treated in our hospital from March 2013 to March 2014 were enrolled. The 106 patients were randomly divided into two groups: observation group and control group Group, the number of patients in each group was 53 cases. Patients in the control group were treated with steroid-oestradiol-depleted pregnancies after curettage surgery, and patients in the observation group were treated with low-dose mifepristone and deoxyestradiol-oestradiol after undergoing curettage surgery. Patients after treatment, the patient’s treatment, endometrial thickness, etc. were compared. Results: After a period of treatment, both groups achieved certain therapeutic effects. The treatment effect of the observation group was more prominent than that of the control group, and the difference between the two groups was statistically significant (P <0.05). Conclusion: After observing the curative effect and each index of two groups of patients, we can see that the treatment effect of the observation group is better. In the treatment of dysfunctional uterine bleeding, the use of low dose of mifepristone combined with deoxynucleotidyl estradiol Good effect, but less side effects, it is worth the clinical application.