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目的 :通过临床应用甘露醇 ,观察其对 1 0 8例恶性肿瘤疼痛的止痛效果及实用性。方法 :ivgtt2 0 %甘露醇 2 5 0ml,随机分为qd组和bid组 ,对两组止痛效果进行比较 ;对恶性肿瘤放射治疗病例 ,分为单纯放射治疗组和放射治疗加ivgtt甘露醇组 ,观察放射治疗引起 4、5、6级疼痛出现率。结果 :ivgtt2 0 %甘露醇 2 5 0ml,qd和bid组 ,止痛效果CR分别为 68 5 %和 70 6% (P >0 0 5 ) ;单纯放射治疗组和放射加ivgtt甘露醇组 ,出现 4、5、6级疼痛率分别为 1 2 5 %和 0 (P <0 0 0 1 )。结论 :ivgtt甘露醇对恶性肿瘤剧痛和放射治疗引起的疼痛均有较好的止痛效果
Objective : To observe the analgesic effect and practicability of 108 cases of malignant tumors by clinical application of mannitol. Methods: ivgtt20% mannitol 250ml was randomly divided into qd group and bid group to compare the analgesic effects of the two groups. For the cases of malignant tumor radiation treatment, they were divided into simple radiotherapy group and radiotherapy plus ivgtt mannitol group. Observed radiotherapy caused grades 4, 5, 6 pain. Results: ivgtt20% mannitol 250ml, qd and bid group, analgesic effect CR were 68.5% and 706% (P > 0 05); radiotherapy alone and ivgtt mannitol group, appeared 4 Grades 5, 6 and 12 had pain rates of 1 25% and 0, respectively (P < 0 0 0 1). Conclusion : ivgtt mannitol has good analgesic effect on pain caused by malignant tumors and radiation therapy.