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目的了解喉癌术后患者医院感染病原菌的临床分离和耐药情况,为临床合理用药及感染控制提供依据。方法通过回顾性调查方法,对某医院住院喉癌手术患者术后医院感染病原菌分离和药敏试验结果进行调查和分析。结果共调查683例喉癌手术患者,发现医院感染88例,感染发生率为12.9%。在感染患者中,肺部感染居首位,构成比占53.4%,主要病原菌为肺炎克雷伯菌,其中产超广谱β-内酰胺酶(ESBLs)菌株占29.03%。其次是手术切口感染,构成比占28.4%,主要病原菌为金黄色葡萄球菌,其中甲氧西林耐药金黄色葡萄球菌(MRSA)菌株占31.25%。结论喉癌术后患者医院感染以肺部和手术切口感染为主,常见病原菌为肺炎克雷伯菌和金黄色葡萄球菌,应有针对性地建立防控措施。
Objective To understand the clinical isolation and drug resistance of nosocomial pathogenic bacteria in postoperative patients with laryngeal cancer and provide the basis for clinical rational drug use and infection control. Methods The retrospective investigation was conducted to investigate the isolation and drug susceptibility test results of nosocomial infection pathogens in hospitalized patients with laryngeal cancer. Results A total of 683 cases of laryngeal cancer surgery were investigated and 88 cases of nosocomial infection were found. The infection rate was 12.9%. Infected patients, lung infection ranked first, accounting for 53.4% of the total composition, the main pathogen Klebsiella pneumoniae, which produce extended-spectrum β-lactamase (ESBLs) strains accounted for 29.03%. Followed by surgical incision infection, the composition ratio accounted for 28.4%, the main pathogen Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA) strains accounted for 31.25%. CONCLUSIONS: Nosocomial infections in patients with laryngeal cancer are mainly pulmonary and surgical incision infections. The common pathogens are Klebsiella pneumoniae and Staphylococcus aureus, and prevention and control measures should be established in a targeted manner.