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本文观察58例急性乙型病毒性肝炎,包括13例暴发性肝炎,说明在急性肝炎最初采血的时间,测定HBeAg血症的重要性。所介绍的急性乙型病毒性肝炎患者都在起病21天之内,13例暴发性肝炎是在起病14天内并已变为肝性脑病Ⅲ~Ⅳ级。两组患者的最初测试HBeAg都在上述早期内,其后每隔3天测定1次,至少随访4周。HBeAg和抗HBe采用标准免疫扩散法测定。患者初期时,其HBsAg(对流电泳CEP)皆阳性,并用补体结合法测滴度。 13例暴发性肝炎中6例(46%)最初血清检出
In this paper, we observed 58 cases of acute hepatitis B, including 13 cases of fulminant hepatitis, indicating the importance of measuring HBeAb during the initial blood sampling of acute hepatitis. The introduced patients with acute hepatitis B are within 21 days of onset, and 13 cases of fulminant hepatitis are within 14 days of onset and have become grade III ~ IV of hepatic encephalopathy. The initial test HBeAg in both groups was in the earlier period and thereafter every 3 days for at least 4 weeks. HBeAg and anti-HBe were measured by standard immunodiffusion. The initial stage of the patient, the HBsAg (convective electrophoresis CEP) were positive, and complement determination of titer. Six out of 13 patients (46%) had initial sera detected