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目的 了解非甲－ 非庚型肝炎患者血清中输血传播病毒（ｔｒａｎｓｆｕｓｉｏｎ ｔｒａｎｓｍｉｔｔｅｄ ｖｉｒｕｓ，ＴＴＶ） 的感染情况及临床特点。方法 用半巢式聚合酶链反应方法检测２０ 例非甲－ 非庚型肝炎患者血清中ＴＴＶ－ ＤＮＡ，特异性引物位于ＴＴＶ基因组的ＯＲＦ１ 保守区。结果 ２０ 例非甲－ 非庚型肝炎患者中，有５ 例存在ＴＴＶ 感染。ＴＴＶ感染者病程有轻有重，表现为急性无黄疸性肝炎、急性黄疸性肝炎及轻度慢性肝炎。结论 非甲－ 非庚型肝炎的患者中存在ＴＴＶ的感染，并可能是致病原因。临床表现为急性或轻度慢性肝炎。ＴＴＶ除血传播外，可能存在肠道传播。
Objective To understand the infection and clinical features of transfusion transmitted virus (TTV) in the serum of non-A-non-G hepatitis patients. Methods TTV-DNA was detected by semi-nested polymerase chain reaction (PCR-RFLP) in 20 patients with non-A and non-G hepatitis, and the specific primers were located in the ORF1 conserved region of TTV genome. Results TTV infection was found in 5 of 20 non-A-non-G hepatitis patients. TTV infection duration of light and heavy, showed no acute jaundice hepatitis, acute jaundice hepatitis and mild chronic hepatitis. Conclusion There is TTV infection in patients with non-A-non-G hepatitis and may be the causative agent. Clinical manifestations of acute or mild chronic hepatitis. TTV in addition to blood transmission, there may be intestinal transmission.