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作者用干扰素损害内注射治疗尖锐湿疣观察其疗效和毒性。用随意、双盲和安慰剂对照的研究方法。79例用活组织检查证实为尖锐湿疣的病人对传统治疗无效。用α—2b、α—nl和β三种干扰素治疗方法。是在疣内用1×10~6干扰素和安慰剂注射,每周三次共4周。干扰素注射后有47％疣完全消退,而用安慰剂注射后仅22％疣完全消退。此外,受干扰素治疗者中,有未受注射的损害的完全消
The author used interferon to injure the condyloma acuminatum to treat the curative effect and toxicity. A randomized, double-blind and placebo-controlled study. 79 patients confirmed by condyloma acuminatum were ineffective with conventional therapy. With α-2b, α-nl and β three kinds of interferon treatment. In the warts with 1 × 10 ~ 6 interferon and placebo injection, three times a week for a total of 4 weeks. Forty-seven percent of warts completely regressed after interferon injection, whereas only 22% of warts completely regressed after placebo injection. In addition, interferon treated patients had complete elimination of uninjured lesions