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目的：探讨急性白血病患者发热时血清粒细胞集落刺激因子（Ｇ—ＣＧＦ）的变化与感染的关系。方法：用ＥＬＩＳＡ方法检测了急性白血病合并感染发热患者血清Ｇ—ＣＳＦ的水平，同时设对照组。结果：对照组血清Ｇ—ＣＳＦ的水平检测全部为阴性；实验组中发热伴细菌培养阳性者血清Ｇ—ＣＳＦ的检测均呈阳性，且血清Ｇ—ＣＳＦ含量与体温呈现正相关；反复感染者急性感染期血清Ｇ—ＣＳＦ水平（ＯＤ值０．１８３±０．０８０）低于非反复感染者同期水平（ＯＤ值０．３８２±０．１６６）；差异显著（Ｐ＜０．０５）。结论：细菌感染是血清Ｇ—ＣＳＦ升高的主要原因
Objective: To investigate the relationship between the change of serum granulocyte colony-stimulating factor (G-CGF) and infection in patients with acute leukemia. Methods: Serum G-CSF levels in patients with acute leukemia complicated with fever were detected by ELISA. Results: The levels of serum G-CSF in the control group were all negative; in the experimental group, the serum G-CSF levels were positive in the fever-positive bacterial cultures, and the serum G-CSF level was positively correlated with the body temperature; Serum G-CSF level (OD value 0.183±0.080) was lower than non-recurrence level (OD value 0.382±0.166) during infection; the difference was significant (P<0.05). Conclusion: Bacterial infection is the main cause of elevated serum G-CSF