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胆道闭锁是一种肝内外胆管出现阻塞并可导致淤胆性肝硬化而最终发生肝功能衰竭的疾患,是小儿外科领域中最重要的消化外科疾病之一,也是小儿肝移植中最常见的适应证。其发生率在东南亚国家为1/9000~1/8000,高于欧美国家的1/15000~1/12000[1-2]。至今病因方面形成一些假说如:胚胎
Biliary atresia is a condition in which the extrahepatic or extrahepatic bile duct obstructs and leads to cholestatic cirrhosis eventually leading to liver failure. It is one of the most important gastrointestinal diseases in pediatric surgery and the most common adaptation in pediatric liver transplantation certificate. Its incidence in Southeast Asian countries for the 1/9000 ~ 1/8000, higher than the European and American countries 1/15000 ~ 1/12000 [1-2]. Etiology has so far formed a number of hypotheses such as: embryos