“Triple-positive” renal limited vasculitis presenting with rapidly progressive glomerulonephritis: A

来源 :急性病杂志(英文版) | 被引量 : 0次 | 上传用户:zouximu19840420
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Rationale: Coexistence of anti-glomerular basement membrane (anti-GBM) disease with anti-neutrophil cytoplasmic antibody (ANCA) in a case of glomerulonephritis is often identified as a “double-positive” disease. Interestingly, the majority of “double positive” ANCA is myeloperoxidase (MPO)-ANCA and some of the MPO-ANCA positive cases showed intrarenal arteritis, suggesting an ANCA-associated kidney lesion. Proteinase 3-ANCA positive diseases are also rarely reported. Patients positive for all three antibodies, i.e., triple-positive patients, are extremely rare.Patient's Concern: A 53 year-old female presented with anasarca and oliguria of 2 months' duration. Diagnosis: Pauci-immune type renal limited crescentic glomerulonephritis positive for MPO-ANCA, proteinase 3-ANCA, and anti-GBM antibody (triple-positive). Interventions: Intravenous high dose cyclophosphamide, oral azathioprine, intravenous methylprednisolone, and plasma exchange as per British Health Professionals in Rheumatology Guidelines. Outcomes: After one-month follow-up, anasarca and proteinuria were lessened, serum creatinine was normalized, titers of MPO-ANCA levels were decreased, and anti-GBM antibody levels were normalized. Lessons: Triple-positive renal limited vasculitis is rare and response to combined immunosuppressive therapy and plasma exchange can contribute to successful remission.
其他文献
记者李梦晓报道也许您有这样的体验,通过Internet打电话时,如使用NetMeeting,总觉得语音时断时续,甚至非常混杂,话音质量不清晰。究其原因,主要是传统路由器不支持语音、图
自发地理信息(Volunteered Geographic Information,VGI)具有覆盖范围广、免费共享、准实时等特点,正迅速成为专业地理信息的重要补充,并得到广泛研究和应用.但由于VGI是由大
时空序列预测分析作为时空数据挖掘中一个重要技术,是对空间上有相互关系的多个时间序列演变趋势与规律进行研究,推测未来时空序列数据的取值或变化趋势.目前,时空序列预测广
  矿产潜力映射是矿产资源勘探与评价中最关键的步骤之一,其旨在在感兴趣区域内通过集成来自地质、地球物理、地球化学以及遥感等方面的信息来圈定成矿远景区。受到探测技术
会议
从前,在北京城里住着一户人家,一个白发苍苍的老奶奶,还有一个叫秀女的姑娘。祖孙两个都是心灵手巧的人,能剪出活灵活现的窗花。光绪年间,有一天从皇宫里传出消息,说是圣母皇
2007年Goodchild提出了志愿者地理信息(Volunteered Geographic Information,VGI)的概念,阐述了在Web2.0环境下,地理信息协作生产和传播共享的问题,用户通过在线协作的方式,
会议
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
“培育和践行社会主义核心价值观”是一项长期的战略任务.文章立足高职院校,分析了当今大学生价值观中存在的主要问题以及高职学生的心理状态,提出了采用德育渗透的方法来推
近几年国家公共机关部门对土地利用、交通、环境等问题越来越重视,也有越来越多的土地利用的微观仿真模型应用于检查和减少城市复杂性的加速增长和政策分析.一般的土地利用模
会议
“V&A”是英国人对“维多利亚与艾伯特博物馆”(Victoria & Albert Museum)的昵称。维多利亚与艾伯特博物馆位于伦敦市中心肯辛顿区的克伦威尔路上。是伦敦四大艺术博物馆之