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眼结膜的细菌感染一般虽具有自限性,但如果能局部应用抗微生物治疗,是可以达到缩短病程,加速治愈的。据近期的美国药物信息,该国药品市场已在出售每ml含0.1％硫酸三甲氧苄氨嘧啶及10000u硫酸多粘菌B溶液,用以治疗眼部浅表性细菌感染。眼科配方中常用的抗菌药物有磺胺醋酰钠、四环素、氯霉素、新霉素等,均存在一定的缺点。如磺胺酷酰钠可致眼痛和罕见的施一约二氏综合征:不少眼科病原体已对四环素产生了耐药性;氯霉素吸收后可能导致罕见的再生障碍性贫血;新霉素可出现局部反应。引起眼结膜感染的常见细菌有肺炎双球菌、金葡菌、流感嗜血杆菌。表皮葡萄球菌常出现在服分泌物中且常并发眼内炎。淋球菌、A族化脓性链球菌及假单胞菌属虽然并不常常引起结膜炎,但其危害性严重,而且可能需要进行全身治疗。
Although the conjunctival bacterial infection in general has a self-limiting, but if topical antimicrobial treatment can be achieved to shorten the course of the disease, accelerate the cure. According to recent U.S. drug information, the drug market in the country is already selling the solution containing trimethoprim 0.1% and polyunsaturase B 10,000 ug per ml for the treatment of superficial bacterial infections of the eye. Ophthalmic formulations commonly used antibacterial drugs are sulfonamide sodium, tetracycline, chloramphenicol, neomycin, etc., there are some shortcomings. Such as sulfonamide sodium can cause eye pain and rare Shiatoshi syndrome: Many ophthalmic pathogens have been resistant to tetracycline; chloramphenicol absorption may lead to rare aplastic anemia; neomycin Partial reaction may occur. Common bacteria that cause conjunctival infection are Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae. Staphylococcus epidermidis often appears in the clothes secretions and often complicated by endophthalmitis. Neisseria gonorrhoeae, Streptococcus pyogenes group A, and Pseudomonas spp., Although not commonly cause conjunctivitis, are highly dangerous and may require systemic treatment.