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为探讨RRI与免疫功能的关系,寻找有效的防治方法,我们对68例(年龄4个月—12岁,平均病程1.5年)每年发生5—16次URRI或3—7次LRRI的患儿,用TF进行防治。3IU/次,im,16—20次为1疗程。随访1年以上,以自身治疗前后变化判定疗效,并观察治疗前后的免疫功能变化。结果:总有效率为92.65％。治疗前患儿CD_3~+、CD_4~+、CD_4~+/CD_8~+、RBC—C_3bR、NKCA和IgG、IgA均显著降低,CD_8~+升高,IgE、IgD、C_3、C_4、RBC—IC等与健康儿无明显差异。治疗后免疫功能失衡状态基本恢复,研究表明:免疫功能紊乱是RRI的重要原因,TF防治RRI有良好效果。
In order to explore the relationship between RRI and immune function and to search for effective prevention and treatment methods, we randomized 68 children (aged 4 months -12 years with an average duration of 1.5 years) to 5-16 URRI or 3-7 LRRI per year, Prevention and treatment with TF. 3IU / time, im, 16-20 times for a course of treatment. Follow-up more than 1 year, to determine the efficacy of their own changes before and after treatment, and observe the changes in immune function before and after treatment. Results: The total effective rate was 92.65%. The levels of CD_3 ~ +, CD_4 ~ +, CD_4 ~ + / CD_8 ~ +, RBC-C_3bR, NKCA and IgG and IgA in children before treatment were significantly decreased, CD8 ~ + increased, IgE, IgD, C_3, C_4 and RBC-IC No significant difference with healthy children. After treatment, the imbalance of immune function basically recovered. Studies have shown that immune dysfunction is an important cause of RRI and that TF is effective in preventing and treating RRI.