Numerical simulation and 3-D periodic flow unsteadiness analysis for a centrifugal pump with volute are carried out in whole flow passage, including the impeller with twisted blades, the volute and the side chamber channels under a part-load condition. The pressure fluctuation intensity coefficient (PFIC) based on the standard deviation method, the time-averaged velocity unsteadi-ness intensity coefficient (VUIC) and the time-averaged turbulence intensity coefficient (TIC) are defined by averaging the results at each grid node for an entire impeller revolution period. Therefore, the strength distributions of the periodic flow unsteadiness based on the unsteady Reynolds-averaged Navier-Stokes (URANS) equations can be analyzed directly and in detail. It is shown that under the des.0.6Q condition, the pressure fluctuation intensity is larger near the blade pressure side than near the suction side, and a high fluctuation intensity can be observed at the beginning section of the spiral of the volute. The flow velocity unsteadiness intensity is larger near the blade suction side than near the pressure side. A strong turbulence intensity can be found near the blade suction side, the impeller shroud side as well as in the side chamber. The leakage flow has a significant effect on the inflow of the impeller, and can increase both the flow velocity unsteadiness intensity and the turbulence intensity near the wall. The accumulative flow unstea-diness results of an impeller revolution can be an important aspect to be considered in the centrifugal pump optimum design for ob-taining a more stable inner flow of the pump and reducing the flow-induced vibration and noise in certain components.