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Poly(C)-binding protein 1(PCBP1 also known as hnRNPEl),a member of the hnRNP family that contains three KH domains,is widely expressed in many human tissues.PCBP1 is known to participate in the regulation of RNA transcription,pre-mRNA processing,maturation,and mRNA export.PCBP1has been reported to play crucial roles in a broad-spectrum of transcriptional and translational events.PCBP1 is also involved in tumor malignancy.Reduced PCBP1 expression may be permissive for HPV proliferation and progression to cervical cancer.Up to now,PCBP expression in cancer cells exposed to
A member of the hnRNP family that contains three KH domains, is widely expressed in many human tissues. PCBBP1 is known to participate in the regulation of RNA transcription, pre- mRNA processing, maturation, and mRNA export .PCBP1has been reported to play crucial roles in a broad-spectrum of transcriptional and translational events. PCBP1 is also involved in tumor malignancy. Reduced PCBP1 expression may be permissive for HPV proliferation and progression to cervical cancer. Up to now, PCBP expression in cancer cells exposed to