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1972年即有人报道再次服用利福平(RFP)引起急性肾功能衰竭。认为多发生在短暂停药之后或间歇治疗中。本文报道1例停药25个月,再次服用 RFP引起急性肾功能衰竭的病例。患者女性,30岁,13岁及15岁时,均因颈淋巴结核而两次用异烟肼(INH)、链霉素(SM)和水杨酸苯胺钙治疗。27岁时再次出现颈淋巴结肿大,每日服用乙胺丁醇(EMB)、INH,RFP。6个月后停用RFP。化疗8个月后出现吞嚥困难。剖胸探查发现纵隔、肺门淋巴结肿大,并有一坏死性后纵隔肿块压追
It was reported in 1972 that once again taking rifampicin (RFP) caused acute renal failure. Think more often after a brief withdrawal or intermittent treatment. This article reports 1 case of withdrawal of 25 months, again taking RFP caused acute renal failure cases. Female patients, 30 years of age, 13 years of age and 15 years of age, were treated with isoniazid (INH), streptomycin (SM), and anilinium salicylate twice for cervical lymph node tuberculosis. Cervical lymph node enlargement occurs again at 27 years of age with daily ethambutol (EMB), INH, and RFP. Disable RFP after 6 months. 8 months after chemotherapy, dysphagia. Thoracotomy revealed mediastinum, hilar lymph nodes, and a necrotic mediastinal mass after chasing