原发性贲门失弛缓症是以下食管括约肌损伤为特征的食管动力性疾病,其治疗方法有气囊扩张和括约肌切开术。这两种方法均是机械扩张括约肌,从而改善食管的排空能力,减缓症状。1993年有人开始报道用肉毒杆菌毒素治疗失弛缓症,疗效较好。本文对30例失弛症病人进行了前瞻性研究,治疗前对病人进行临床症状评估,均行胃肠道内镜和钡餐检查,并测量食管压力。 Primary achalasia is a esophageal motility disorder characterized by the following esophageal sphincter injuries, with balloon dilation and sphincterotomy. Both of these methods mechanically expand the sphincter, thereby improving esophageal emptying ability and alleviating symptoms. Someone started to report the treatment of achalasia with botulinum toxin in 1993, and the curative effect is better. In this paper, 30 cases of patients with achalasia were prospectively studied. Before treatment, patients were evaluated for clinical symptoms. Gastrointestinal endoscopy and barium meal examination were performed and esophageal pressure was measured.