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目的探讨尿毒症患者继发动脉粥样硬化性心血管合并症的危险因素。方法观测３２例尿毒症，２６例慢性肾小球肾炎患者血清甘油三脂、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、ａｐｏＡ１、ａｐｏＢ水平，计算ａｐｏＡ１／ａｐｏＢ比值，并与３０名健康人作对比分析。结果尿毒症患者血清甘油三脂、总胆固醇正常，高密度脂蛋白胆固醇、ａｐｏＡ１降低，低密度脂蛋白胆固醇、ａｐｏＢ升高，ａｐｏＡ１／ａｐｏＢ降低。结论尿毒症患者血清载脂蛋白异常，是诱发动脉粥样硬化性心血管合并症的高危因素
Objective To investigate the risk factors of secondary atherosclerotic cardiovascular complications in uremic patients. Methods Serum triglycerides, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, apoA1 and apoB levels were measured in 32 uremic patients and 26 chronic glomerulonephritis patients. The apoA1 / apoB ratios were calculated and compared with 30 Healthy people for comparative analysis. Results Serum triglyceride, total cholesterol, high density lipoprotein cholesterol, apoA1, low density lipoprotein cholesterol, apoB, apoA1 / apoB decreased in uremic patients. Conclusion Uremic patients with serum apolipoprotein abnormalities are risk factors for atherosclerotic cardiovascular comorbidity