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1995年,上村及其合作者从水产贝类动物多棘裂江珧(Pinnamuricata)分离出江珧毒素A(1),并测定全部结构和相对立体化学,还指出了生物合成的途径,即2→1。在中国和日本,江珧毒素A是引起江珧贝类中毒的主要毒素之一,其独特的分子结构和显著的激活Ca2+通道的生物活性,激
In 1995, Shangcun and his collaborators isolated Gingotoxin A (1) from Pinnamuricata, a marine shellfish species, and determined the overall structure and relative stereochemistry. It also pointed out the pathway for biosynthesis. →1. In China and Japan, G. hirsutum A is one of the main toxins causing G. striata poisoning, its unique molecular structure and the remarkable activation of Ca2+ channel biological activity.