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肿瘤是由基因突变引起 ,基因突变可由致癌剂引起 ,也可由DNA代谢过程中的碱基错配引起 ,为保证遗传物质的完整性和稳定性 ,细胞有许多防止基因突变的系统。这些系统包括①切除修复②损伤碱基的直接修复③错配修复④重组修复⑤跨损伤DNA合成。错配修复基因能纠正由于DNA重组和复
Tumors are caused by genetic mutations. Mutations can be caused by carcinogens. They can also be caused by base mismatches in DNA metabolism. To ensure the integrity and stability of genetic material, cells have many systems that prevent gene mutations. These systems include ① excision repair ② direct repair of damaged bases ③ mismatch repair ④ recombinant repair ⑤ cross-damage DNA synthesis. Mismatch repair genes can be corrected due to DNA recombination and recombination