论文部分内容阅读
目的研究超微粉碎前后川芎的粉体学性质,为超微粉碎对含挥发油类药材的影响提供依据。方法采用激光粒度分析仪测定粉末粒径及粒度分布;生物显微镜进行显微学研究;测定粉体休止角和堆密度,测定25℃相对湿度为75%条件下粉体的吸湿性。结果 川芎超微粉和普通粉的D50分别为14.58、58.54μm,且超微粉粒度分布均匀性较好;显微镜下可见超微粉和普通粉在显微特征上都有较大的区别,油滴显著减小;超微粉碎对川芎粉体的流动性、堆密度和吸湿性没有显著的影响。结论超微粉碎后细胞破壁率显著增大,均匀度得到改善,其中油滴的显著减小为挥发油类药材超微粉碎形成“乳化结构”的证实提供了初步的依据和借鉴。流动性、堆密度和吸湿性无显著变化,说明富含挥发油的川芎在粉体学性质上有其特殊性。
Objective To study the powder properties of Chuanxiong before and after ultrafine pulverization to provide basis for the effect of ultrafine pulverization on volatile oil-containing medicinal materials. Methods The laser particle size analyzer was used to determine the particle size and particle size distribution. Microscopy was carried out with a biological microscope. The angle of repose and the bulk density of the powder were measured. The hygroscopicity of the powder was measured at 25% relative humidity of 75%. Results The D50 of the ultrafine powder and ordinary powder of Chuanxiong was 14.58,58.54μm, respectively, and the particle size distribution uniformity of the superfine powder was good. The microscopic examination showed that the ultrafine powder and common powder had significant difference in microscopic features, Small; ultrafine pulverization had no significant effect on the fluidity, bulk density and hygroscopicity of Chuanxiong powder. CONCLUSION: The cell breakage rate increased and the evenness was improved after ultrafine comminution. The significant decrease of oil droplets provided the preliminary evidence and reference for the confirmation of the microemulsification of volatile oil medicinal materials. Liquidity, bulk density and hygroscopicity showed no significant change, indicating that the volatile oil-rich Chuanxiong has its peculiarities in powder science.