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目的:研究脂微球前列腺素E1(凯时,Lipo PGE1)在室间隔缺损并重度肺动脉高压的围手术期的应用。方法:收治32例室缺合并重度肺动脉高压病例,给予凯时治疗比较用药前后各指标的变化。结果:应用凯时可改善患者的氧饱和度、氧分压、降低肺动脉压,而对系统血压及心率无明显影响。结论:围手术期应用凯时疗效显著,不良反应小。
OBJECTIVE: To study the perioperative application of liposomal prostaglandin E1 (Lipo PGE1) in patients with ventricular septal defect and severe pulmonary hypertension. Methods: Thirty-two cases of ventricular septal defect complicated with severe pulmonary hypertension were treated, and the changes of each index before and after the treatment were compared. Results: The application of Kay when patients can improve oxygen saturation, partial pressure of oxygen, reduce pulmonary artery pressure, while the system of blood pressure and heart rate had no significant effect. Conclusion: Perioperative application of Kay significant effect, adverse reactions.