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康达饮是一种中药排铅饮料。SD大鼠饮用含醋酸铅饮水后制成铅中毒模型,并根据血铅水平随机分成高、低康达饮实验组和阳性对照组,另设空白对照组,每组20只,雌雄各半。两康达饮组动物每天用高、低剂量的康达饮灌胃,实验期三个月。在不同时间测血铅、尿铅、骨铅、ZPP和Hb等指标。结果显示康达饮可增加大鼠尿铅的排出(P<0.05),降低骨铅贮量(P<0.05)。但血铅水平轻度提高(P=0.29),这可能是因为骨铅释出增加或进入骨内铅减少所致。本实验表明康达饮有一定的排铅效果,可降低机体的铅负荷。
Kangda drink is a traditional Chinese medicine row of lead drinks. SD rats drinking lead acetate drinking water into lead poisoning model, and according to blood lead levels were randomly divided into high and low Kangda drink experimental group and positive control group, another set of blank control group, 20 in each group, male and female. Two Kangda drink animals daily with high and low doses of Kang Da drink stomach, the experimental period of three months. Blood lead, urine lead, bone lead, ZPP and Hb were measured at different times. The results showed that Kangda drink can increase urinary lead excretion (P <0.05) and decrease bone lead (P <0.05). However, blood lead levels increased slightly (P = 0.29), possibly due to increased bone lead release or decreased lead into the bone. This experiment shows that Kangda drinking lead discharge effect, can reduce the body’s lead load.