目前较常用的抗焦虑药苯二氮卓类(Benzodiazepines)是发展很快的一类药物,在临床应用已有10种以上;苯二氮卓类药物的典型代表为安定及利眠宁,具有镇静、抗焦虑、抗惊厥和中枢性肌肉松弛等广泛的药理作用。这类药物的特点是毒性低(服用剂量达到治疗量的数百倍时也不出现中毒症状),存在生理依赖性(停药后可出现戒断症状)及作用广泛,提示它不是简单的中枢神经系统抑制剂,而可能是一类神经调节物质。然 Benzodiazepines, the most commonly used anxiolytic drugs, are a kind of rapidly developing drugs and have been used clinically for more than 10 times. Typical representatives of benzodiazepines are diazepam and lirimoning, Sedative, anti-anxiety, anticonvulsant and central muscle relaxation and a wide range of pharmacological effects. Such drugs are characterized by low toxicity (no symptoms of poisoning when doses reach a few hundredth of the therapeutic dose), physiological dependence (with withdrawal symptoms after discontinuation) and a broad range of effects suggesting that it is not a simple central Neurological inhibitors, but may be a class of neuromodulators. Of course