本世纪初,人们已知与抗体有关的肾小球肾炎(简称肾炎)具有两种不同的发病机制。一种是循环中的抗体与肾小球基底膜上的抗原相结合引起炎性反应,称为抗肾小球基底膜抗体性肾炎(简称抗肾抗体肾炎)。另一种是循环中的抗体与存在于循环中的非肾小球基底膜抗原相结合形成可溶性免疫复合物,然后沉积在肾小球上并引起炎性反 The beginning of this century, it is known that antibody-related glomerulonephritis (referred to as nephritis) has two different pathogenesis. One is the circulation of antibodies and glomerular basement membrane antigen on the combination of inflammatory response, known as anti-glomerular basement membrane antibody nephritis (anti-renal antibody nephritis). The other is that circulating antibodies bind to non-glomerular basement membrane antigens present in the circulation to form soluble immune complexes, which are then deposited on glomeruli and cause inflammatory responses