多发性骨髓瘤引起血型鉴定和配血困难的病例多有报道 ,但分析血型正反定型不符原因时 ,发现多发性骨髓瘤的报道较少 ,现将我院发现的 3例报道如下 :1　临床资料　　病例 1:男性 ,6 2岁 ,1998年 3月因发生原因不明的反复腰痛 ,严重贫血貌 ,以贫血原因待查入院 ,查Ｈｂ5 2ｇ/Ｌ , Many cases of blood group identification and dysphagia caused by multiple myeloma have been reported. However, when the reasons for the discrepancy between the positive and negative stereotypes of the blood group were analyzed, multiple reports of multiple myeloma were found. The three cases reported in our hospital are reported as follows: 1 Clinical Data Case 1: Male, 62 years old, March 1998 due to unexplained recurrent low back pain, severe anaemia appearance, reason for anemia to be admitted to hospital, check Hb5 2g/L,