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目的:在对患者施行动脉导管未闭(PDA)封堵术后对患者血小板减少的原因进行分析,并提出相应的防治措施。方法:选择在我院施行PDA封堵术后出现血小板减少的患者共计20例,对患者血小板减少的时间,残余分流、下降的规律以及之防治措施等进行分析并探讨。结果:经检查,所有患者均为巨大PDA患者,在完成手术后均存在着程度不同的分流,在完成封堵后的3天内出现血小板减少的情况,在手术后4d至6d之间血小板最低,其中有12例患者需进行血小板的输注,所有患者均未出现严重的内脏出血。结论:在实行PDA封堵术后患者出现血小板减少的情况属于发生率较低的并发症状,发病原因主要同残余分流而导致的机械性破坏存在着关联,仅有少数患者需要补充血小板进行治疗。
OBJECTIVE: To analyze the causes of thrombocytopenia in patients with patent ductus arteriosus (PDA) and to put forward the corresponding prevention and treatment measures. Methods: A total of 20 patients with thrombocytopenia who underwent PDA occlusion in our hospital were selected and analyzed. The duration of thrombocytopenia, residual shunting and declining, and the prevention and treatment measures were analyzed and discussed. Results: All patients were classified as giant PDA patients. All patients had varying degrees of shunting after completion of the procedure. Thrombocytopenia occurred within 3 days after closure. Platelets were the lowest between 4 and 6 days after surgery, Twelve of these patients required platelet transfusions and none of the patients had severe visceral hemorrhage. CONCLUSIONS: Thrombocytopenia in patients undergoing PDA occlusion is associated with lower incidence of complications associated with mechanical disruption due to residual shunts. Only a minority of patients require platelet replacement therapy.