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Trimetrexate(TMTX)是一种有效的脂溶性抗叶酸盐,体外实验已证实其具有强大的抑制二氢叶酸还原酶的功能,其抑制作用分别比乙胺嘧啶、甲氧苄氨嘧啶(TMP)大
Trimetrexate (TMTX) is a potent, fat-soluble, antifolate that has been shown to exert its potent inhibitory effect on dihydrofolate reductase in vitro and its inhibitory effect compared to pyrimethamine, trimethoprim (TMP) Big