硝苯吡啶是一种钙通道阻滯剂,对动脉血管壁平滑肌细胞膜钙通道具有高度选择性,它可阻止钙进入平滑肌细胞,并阻止钙从肌浆网进入肌浆,使兴奋收缩偶联减弱,扩张体循环血管,减低外周血管阻力,从而起到降压作用。硝苯吡啶舌下含服能被粘膜迅速吸收,5～10分钟即可发挥快速降压作用,对高血压急症有理想的实用价值。笔者于1987年4～11月观 Nifedipine is a calcium channel blocker that is highly selective for the calcium channels of the arterial wall smooth muscle cell membrane and prevents calcium from entering the smooth muscle cells and preventing calcium from sarcoplasmic reticulum from entering the sarcoplasm, weakening the excitation-contraction coupling , The expansion of systemic circulation of blood vessels, reduce peripheral vascular resistance, which play a role in antihypertensive. Nifedipine sublingual can be quickly absorbed mucosa, 5 to 10 minutes to play a rapid antihypertensive effect of hypertensive emergency has an ideal practical value. The author from April to November 1987 concept