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近年来,核磁共振用于肿瘤研究引起了广泛注意。Damadian等曾用1~H脉冲核磁共振测定了正常大鼠及接种Walker肉瘤与Novikoff肝癌大鼠各种组织的自旋-晶格弛予时间T_1及自旋-自旋弛予时间T_2,发现用T_1及T_2的测定值可以鉴别癌组织与正常组织。其后,将此技术用于活鼠尾部的黑色素瘤测定,为核磁共振直接研究活体开辟了新途径。继之,Hollis等又对人体各种组织作了测定,亦得到类似结果。
In recent years, NMR has been used extensively for tumor research. Damadian et al. used the 1H pulsed NMR to determine the spin-lattice relaxation time T_1 and the spin-spin relaxation time T_2 of normal rats and rats transplanted with Walker sarcoma and Novikoff liver cancer. The measured values of T_1 and T_2 can identify cancerous tissue and normal tissue. Later, this technique was applied to the determination of melanoma in the tail of living mice, opening up a new way for MRI to study living organisms directly. Following this, Hollis et al. also measured various tissues of the human body and obtained similar results.