论文部分内容阅读
目的:调查湖北地区性滥者和药瘾者HGV感染状况及其影响因素。方法:检查药瘾者和性滥者的血清HGV感染指标,用ELISA法检测抗HGV。结果:2206例标本中普通健康体检者1257例;949例为特殊人群(药隐者716例,性滥者309例,其中76例既是药瘾者又是性滥者),其HGV感染率分别为12.85%(75/716)、11.97%(20/309)、22.37%(17/76),均显著高于普通人群(1.51%,19/1257)。药瘾和性滥2年以上者抗HGV阳性率(19.41%,17.05%)显著高于药瘾和性滥2年以下者(8.01%,5.26%;χ2分别为19.29和8.89,P<0.01);静脉药瘾者抗HGV阳性率(16.96%)与口服药瘾者(5.73%)比较差异有显著性意义(χ2=108.31,P<0.05);性别和HBV感染对药瘾和性滥者抗HGV阳性率的高低没有影响(χ2分别为1.36和1.59,P>0.05);抗HCV(+)者和抗HCV(-)者的抗HGV阳性率差异有显著性意义(χ2分别为19.26和4.25,P<0.05)。所有HGV感染者的肝功能正常。结论:药瘾者和性滥者均具有较高的HGV感染率。其HGV感染率与吸毒时间或性滥时间呈正相关。
Objective: To investigate the prevalence and influencing factors of HGV among abused and drug addicts in Hubei Province. Methods: The indexes of serum HGV infection among drug addicts and abuser were examined, and anti-HGV was detected by ELISA. Results: Among the 2206 specimens, there were 1257 general health examination subjects, 949 special treatment groups (716 cases of drug abusers, 309 aggressive subjects, of which 76 were both addicts and abscess). The prevalence of HGV infection was 12.85% (75/716), 11.97% (20/309) and 22.37% (17/76) respectively, which were all significantly higher than the general population (1.51%, 19/1257). The anti-HGV positive rate (19.41%, 17.05%) was significantly higher than that of drug addicts and abuse over two years (8.01%, 5.26%; χ2 = 19.29 and 8.89, P <0.01) ; The positive rate of anti-HGV (16.96%) in intravenous drug addicts was significantly different from that of oral drug addicts (5.73%) (χ2 = 108.31, P <0.05) The positive rate of HGV had no effect (χ2 = 1.36 and 1.59, P> 0.05). There was significant difference in the positive rate of anti-HGV between anti-HCV (+) and anti-HCV , P <0.05). All HGV infected people had normal liver function. Conclusion: Both drug addicts and abuser have higher rates of HGV infection. The HGV infection rate and drug abuse time or sexual abuse time was positively correlated.