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萝芙木为治疗高血压病的药物,含有数十种生物碱,其中利血平(reserpine)具有显著降压作用,锐西胺(rescinnamine)及坎尼生(canescine)与利血平结构相近,也具有类似的降压作用。用纸上电泳不能使它们分离;纸层析及柱层析则费时费事;薄层层析可将利血平及锐西胺分开而未见有与坎尼生分开的报道。本文采用分配薄层层析作三者的分离。曾试用了氧化铝、硅胶、硅藻土及纤维素为支持剂、甲酰胺为固定相以及数十种溶剂系统进行研究,结果以纤维素薄层分
Rauvolfia is a drug for the treatment of hypertension, and contains dozens of alkaloids, of which reserpine has a significant antihypertensive effect. The structure of rescinnamine and canescine is similar to that of reserpine , Also has a similar antihypertensive effect. Electrophoresis on paper can not separate them; paper chromatography and column chromatography are time-consuming; thin-layer chromatography separates reserpine and bethanein and no separate reports from cannix are available. In this paper, the distribution of TLC for the three separation. Have tried alumina, silica gel, diatomaceous earth and cellulose as a support agent, formamide as a stationary phase and dozens of solvent systems were studied, the results of the thin layer of cellulose