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二、小分子化合物 1．EGFR酪氨酸激酶抑制剂 (1)吉非替尼(Gefitinib),商品名易瑞沙(Iressa) 吉非替尼是一种可以口服的苯胺喹唑啉类小分子化合物-EGFR酪氯酸激酶抑制剂(TKIs),作用靶点是酪氯酸蛋白激酶(PTK),用来治疗非小细胞肺癌(NSCLC)和其他肿瘤如结直肠癌、头颈部癌、前列腺癌等。在各种肿瘤患者中进行的临床试验结果显示其具有较好的临床效果和良好的耐受性。其对单药治疗铂类为主化疗
Second, small molecule compounds 1. EGFR Tyrosine Kinase Inhibitors (1) Gefitinib, Iressa Gefitinib is an oral aniline quinazoline class of small molecule compounds - EGFR tyrosine kinase Inhibitors (TKIs) targeting tyrosine kinase (PTK) are used to treat non-small cell lung cancer (NSCLC) and other tumors such as colorectal cancer, head and neck cancer and prostate cancer. The results of clinical trials conducted in various cancer patients show that it has good clinical effect and good tolerability. Its monotherapy platinum-based chemotherapy