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目的：优选山豆根药材的提取工艺。方法：以提取物中苦参碱的含量为研究指标，采用高效液相色谱法测定其含量；比较水提醇沉法、60℃酸水浸泡醇沉，pH8-9氨水提取醇沉法、60%乙醇加热回流法等不同工艺的差异。结果：60%乙醇加热回流法苦参碱含量较高，苦参碱含量在6.24μg～399.04μg范围里呈较好的线性关系；苦参碱的回收率为100.08%。结论：60%乙醇加热回流法，提取山豆根药材的提取物中苦参碱含量较高，苦参碱转移率最高，提取方法合理、操作简单，适合用于大生产提取工艺。“,”Objective: To optimize the extraction technology for the Sophorae Tonkinensis Radix Et Rhizoma. Methods: Taking the content of the Matrine within the extracts as a study index, we use HPLC to determine its content. Then we compare differences among Water extraction - Alcohol precipitation,60℃Acid water soaking- Alcohol precipitation,pH8-9 Ammonia water extraction Alcohol precipitation and 60% Alcohol Heating reflux method.Result: The content of the Matrine from 60% Alcohol Heating reflux method is the higher.In the range of 6.24μg~399.04μg,the content of the Matrine shows a good linear relationship and the recovery is 100.08%.Conclusion: Using the 60% alcohol Heating reflux method, the content of the Matrine from the Sophorae Tonkinensis Radix Et RhizomaExtracts is the higher, with a highest metastasis rate. The extracting method is reasonable, simple and suitable for industrialized production.