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目的:观察通心络胶囊治疗糖尿病足的临床疗效及其作用机制的探讨。方法:在血糖控制、改善微循环等全面治疗的基础上,将所有入选患者随机分为通心络治疗组32例,常规治疗组30例,治疗组外用及口服通心络,比较治疗前后两组的血液流变学指标、以及肌电图的感觉、运动神经传导速度的变化。结果:通心络治疗组总有效率为96.87%,常规治疗组总有效率为80.00%,通心络治疗组显著优于常规治疗组(P<0.01);血黏度均显著下降;感觉、运动传导速度均显著改善,很优于对照组(P<0.01)。结论:通心络对治疗糖尿病足有良好效果。
Objective: To observe the clinical efficacy of Tongxinluo capsule in the treatment of diabetic foot and its mechanism of action. Methods: On the basis of comprehensive treatment such as blood glucose control and microcirculation improvement, all the patients were randomly divided into Tongxinluo treatment group (32 cases), conventional treatment group (30 cases), treatment group (30 cases) and oral Tongxinluo Group of hemorheological parameters, as well as the feeling of EMG, motor nerve conduction velocity changes. Results: The total effective rate was 96.87% in Tongxinluo group and 80.00% in routine treatment group. Tongxinluo treatment group was significantly better than conventional treatment group (P <0.01), blood viscosity was significantly decreased, sensory and motor The conduction velocity was significantly improved, which was better than the control group (P <0.01). Conclusion: Tongxinluo treatment of diabetic foot has a good effect.