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目的:评价天舒胶囊联合西酞普兰治疗慢性原发性头痛的疗效。方法:在门诊及病房工作中收集原发性头痛患者,以区组随机法随机分为治疗组40例(天舒胶囊、西酞普兰)和对照组43例(丙戊酸钠、阿米替林),分别于治疗初进行头痛程度的评分及生活质量综合评分,然后于治疗后2周、4周复查头痛程度的评分及生活质量综合评分。结果:治疗后两组患者的头痛程度均有改善,治疗组疗效优于对照组。治疗组患者的生活质量改善程度优于对照组。治疗组患者的药物不良反应发生率低于对照组。结论:天舒胶囊联合西酞普兰治疗原发性头痛安全有效。
Objective: To evaluate the efficacy of Tianshu capsule combined with citalopram in the treatment of chronic primary headache. Methods: Patients with primary headache were collected in outpatient and ward work. Patients were randomly divided into treatment group of 40 cases (Tianshu capsule and citalopram) and control group (sodium valproate, The scores of headache degree and comprehensive quality of life score were evaluated at the beginning of treatment, then the scores of headache degree and comprehensive quality of life score were reviewed at 2 weeks and 4 weeks after treatment. Results: The degree of headache in both groups improved after treatment, and the curative effect in treatment group was better than that in control group. The quality of life of the treatment group improved better than the control group. The incidence of adverse drug reactions in the treatment group was lower than that in the control group. Conclusion: Tianshu capsule combined with citalopram in the treatment of primary headache is safe and effective.